The story of vaccines did not begin with the first vaccine which was Edward Jenner’s vaccine to provide protection against smallpox. Rather, it begins with the long history of infectious disease in humans, and in particular, with early uses of smallpox material to provide immunity to that disease.
Evidence exists that the Chinese employed smallpox inoculation as early as 1000 CE. It was practiced in Africa and Turkey as well, before it spread to Europe and the Americas.
Edward Jenner’s innovations, begun with his successful 1796 use of cowpox material to create immunity to smallpox, quickly made the practice widespread. His method underwent medical and technological changes over the next 200 years, and eventually resulted in the eradication of smallpox.
Louis Pasteur’s 1885 rabies vaccine was the next to make an impact on human disease. And then, at the dawn of bacteriology, developments rapidly followed. Antitoxins and vaccines against diphtheria, tetanus, anthrax, cholera, plague, typhoid, tuberculosis, and more were developed through the 1930s.
The middle of the 20th century was an active time for vaccine research and development. Methods for growing viruses in the laboratory led to rapid discoveries and innovations, including the creation of vaccines for polio. Researchers targeted other common childhood diseases such as measles, mumps, and rubella, and vaccines for these diseases reduced the disease burden greatly.
Innovative techniques now drive vaccine research, with amazing DNA technology and new delivery techniques leading scientists in new directions. Disease targets have expanded, and some vaccine research is beginning to focus on non-infectious conditions such as addiction and allergies.
Due to the Coronavirus pandemic scientists have had to look into a vaccine for that and luckily this is now becoming available.
The elderly are being vaccinated early to help protect them and to minimise the damage that COVID-19 can do so if you haven’t had yours yet it won’t be long!
